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硕士生导师

闵远琴

来源: 时间:2023-04-27
 


姓       名: 闵远琴

职称职务: 副研究员

电子邮箱:minyuanqin@wh.iov.cn

研究方向

病毒-宿主互作网络

抗病毒药物、疫苗

教育及工作经历

教育经历

2011.08-2015.12,武汉大学,医学博士

2008.09-2011.07,东北林业大学,理学硕士

2004.09-2008.07,安徽师范大学,理学学士

工作经历

2022.11-至今,中国科学院武汉病毒研究所,副研究员

2020.06-2022.11,中国科学院武汉病毒研究所,助研

2016.08-2020.06,中国科学院武汉病毒研究所,博士后

近五年承担项目

1. 天然免疫信号蛋白MAVS在新布尼亚病毒SFTSV诱导炎症反应中的作用及机研究,主持,国家级,2018-01—2020-12

2. 消毒液、滤料等对新冠灭活能力的研究,主持,企业委托,2020-06--2020-12

3. 新型布尼亚病毒(SFTSV-Like)结构蛋白(SP/GP)线性抗原表位及其自然疫源性研究,参与,国家级,2018-01—2020-12

近五年代表性论文

1.  Min YQ, Ning YJ, Wang H, Deng F. 2020. A RIG-I-like receptor directs antiviral responses to a bunyavirus and is antagonized by virus-induced blockade of TRIM25-mediated ubiquitination. J Biol Chem 295:9691-9711.

2. Min YQ, Shi C, Yao T, Feng K, Mo Q, Deng F, Wang H, Ning YJ. 2020. The Nonstructural Protein of Guertu Virus Disrupts Host Defenses by Blocking Antiviral Interferon Induction and Action. ACS Infect Dis 6:857-870.

3.  Min YQ#, Huang M#, Sun X, Deng F, Wang H, Ning YJ. 2021. Immune evasion of SARS-CoV-2 from interferon antiviral system. Comput Struct Biotechnol J 19:4217-4225.

4.  Min YQ#, Mo Q#, Wan J, Deng F, Wang H, Ning YJ. 2020. SARS-CoV-2 nsp1: Bioinformatics, Potential Structural and Functional Features, and Implications for Drug/Vaccine Designs. Front Microbiol 2020, 11.

5.  Feng K#, Min YQ#, Sun X, Deng F, Li P, Wang H, Ning YJ. 2021. Interactome profiling reveals interaction of SARS-CoV-2 NSP13 with host factor STAT1 to suppress interferon signaling. J Mol Cell Biol.  (共一)

6.   Sun J#, Min YQ#, Li Y, Sun X, Deng F, Wang H, Ning YJ. 2021. Animal Model of Severe Fever With Thrombocytopenia Syndrome Virus Infection. Front Microbiol 12:797189. (共一)

7. Hu J#, Min YQ#, Sun X. 2022. Cis-regulatory decoy disrupts autorepression: a potential escape-resistant anti-viral therapy. Signal Transduct Target Ther 7:338. (共一)

8.  Zhang J, Hu Z, He J, Liao Y, Li Y, Pei R, Fang X, Zeng P, Fan R, Ou Z, Deng J, Zhou J, Guan W, Min YQ, Deng F, Peng H, Zhang Z, Feng C, Xin B. 2021. Safety and immunogenicity of a recombinant interferon-armed RBD dimer vaccine (V-01) for COVID-19 in healthy adults: a randomized, double-blind, placebo-controlled, Phase I trial. Emerg Microbes Infect 10:1589-1597.

9.  Ning YJ, Kang Z, Xing J, Min YQ, Liu D, Feng K, Wang M, Deng F, Zhou Y, Hu Z, Wang H. 2018. Ebola virus mucin-like glycoprotein (Emuc) induces remarkable acute inflammation and tissue injury: evidence for Emuc pathogenicity in vivo. Protein Cell 9:389-393.

 

 

 

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