陈建军

姓   名：陈建军

职称职务：研究员、博导

电子邮箱：chenjj@wh.iov.cn

研究方向

1、流感病毒及呼吸道病毒流行规律及生态分布研究

2、流感病毒通用及新型疫苗研究

教育及工作经历

1996.9-2000.6 湖南师范大学生科院 生物教育专业 学士学位

2000.9-2003.6 湖南师范大学生科院 生物化学与分子生物学专业 硕士学位

2005.9-2008.6 中国科学院武汉病毒所 微生物专业 博士学位

2003.7-2005.12 中科院武汉病毒所 实习研究员

2005.12-2010.12中科院武汉病毒所 助理研究员

2010.12-2020.8 中科院武汉病毒所 副研究员

2011.6-2011.10 美国Emory大学 微生物与免疫学系 博士后

2020.9--             中科院武汉病毒所 研究员

近五年承担项目

1.湖北及周边省传染病病原谱和流行规律研究/传染病重大专项/2017-2020/课题负责

2.新型冠状病毒追踪及环境风险评估/重点研发计划/2020.1-2020.12/课题负责

3.青海湖禽流感病毒动态流行及病毒多样性研究/NSFC-面上/2020-2023/主持

4.中俄高致病性禽流感及其它禽类病毒的流行及跨洲传播研究/NSFC-国际合作/2020-2022/主持

5.武汉沉湖湿地候鸟、留鸟和家禽间禽流感病毒的传播/国家自然科学基金面上项目/2016-2019/主持；

近五年代表性论文

1.  Chen J#, Huang C, Zhang Y, Zhang S, Jin M. Severe Acute Respiratory Syndrome Coronavirus 2-Specific Antibodies in Pets in Wuhan, China. J Infect. 2020 Sep;81(3):e68-e69.

2.  Zheng X, Wang H, Su Z, Li W, Yang D, Deng F#, Chen J#. Co-infection of SARS-CoV-2 and Influenza virus in Early Stage of the COVID-19 Epidemic in Wuhan, China. J Infect. 2020 Aug;81(2):e128-e129.

3.  Fadlallah GM, Ma F, Zhang Z, Hao M, Hu J, Li M, Liu H, Liang B, Yao Y, Gong R, Zhang B, Liu D, Chen J#. Vaccination with Consensus H7 Elicits Broadly Reactive and Protective Antibodies against Eurasian and North American Lineage H7 Viruses. Vaccines (Basel). 2020 Mar 23;8(1):143.

4.  Jia L, Jiang M, Wu K, Hu J, Wang Y, Quan W, Hao M, Liu H, Wei H, Fan W, Liu W, Hu R, Wang D, Li J#, Chen J#, Liu D#. Nanopore sequencing of African swine fever virus. Sci China Life Sci. 2020 Jan;63(1):160-164.

5.  Li M, Chen L, Wang Q, Hao M, Zhang X, Liu L, Yu X, Yang C, Xu J#, Chen J#, Gong R#. A cross-reactive human monoclonal antibody targets the conserved H7 antigenic site A from fifth wave H7N9-infected humans. Antiviral Res. 2019 Jul 9;170:104556.

6.  Chen J*#, Liang B*, Hu J, Liu H, Sun J, Li M, Chen Q, He Y, Liu D#. Circulation, Evolution and Transmission of H5N8 virus, 2016-2018. J Infect. 2019 Jul 12. pii: S0163-4453(19)30214-2.

7.  Yao Y, Wang H, Chen J#, Shao Z, He B, Chen J, Lan J, Chen Q & Chen Z. Protection against homo and hetero-subtypic in？uenza A virus by optimized M2e DNA vaccine. Emerg Microbes Infect. 2019; 8:1, 45-54.

8.  Liu H, Xiong C, Chen J, Chen G, Zhang J, Li Y, Xiong Y, Wang R, Cao Y, Chen Q, Liu D, Wang H, Chen J#. Two genetically diverse H7N7 avian influenza viruses isolated from migratory birds in central China. Emerg Microbes Infect. 2018 Apr 11;7(1):62.

9.  Qi M, Zhang XE, Sun X, Zhang X, Yao Y, Liu S, Chen Z, Li W, Zhang Z, Chen J#, Cui Z#. Intranasal Nanovaccine Confers Homo- and Hetero-Subtypic Influenza Protection. Small. 2018 Mar;14(13):e1703207.

10.Bi Y*, Chen Q*, Wang Q*, Chen J*, Jin T, Wong G, Quan C, Liu J, Wu J, Yin R, Zhao L, Li M, Ding Z, Zou R, Xu W, Li H, Wang H, Tian K, Fu G, Huang Y, Shestopalov A, Li S, Xu B, Yu H, Luo T, Lu L, Xu X, Luo Y, Liu Y#, Shi W#, Liu D#, Gao GF#. Genesis, Evolution and Prevalence of H5N6 Avian Influenza Viruses in China. Cell Host Microbe. 2016 Dec 14;20(6):810-821.

11.Li M, Liu H, Bi Y, Sun J, Wong G, Liu D, Li L, Liu J, Chen Q, Wang H, He Y, Shi W, Gao GF, Chen J#. Highly Pathogenic Avian Influenza A(H5N8) Virus in Wild Migratory Birds, Qinghai Lake, China. Emerg Infect Dis. 2017 Apr;23(4):637-641.

12.Wu M, Zhang ZL, Chen G, Wen CY, Wu LL, Hu J, Xiong CC, Chen JJ#, Pang DW#. Rapid and Quantitative Detection of Avian Influenza A(H7N9) Virions in Complex Matrices Based on Combined Magnetic Capture and Quantum Dot Labeling. Small. 2015 Oct 21;11(39):5280-8.

13.Wu Z, Zhou CH, Chen JJ#, Xiong C, Chen Z, Pang DW, Zhang ZL#. Bifunctional magnetic nanobeads for sensitive detection of avian influenza A (H7N9) virus based on immunomagnetic separation and enzyme-induced metallization. Biosens Bioelectron. 2015 Jun 15;68:586-592.

14.Hu J, Jiang YZ, Wu LL, Wu Z, Bi Y, Wong G, Qiu X, Chen J#, Pang DW, Zhang ZL#. Dual-Signal Readout Nanospheres for Rapid Point-of-Care Detection of Ebola Virus Glycoprotein. Anal Chem. 2017 Dec 19;89(24):13105-13111.

15.Bi Y, Liu H, Xiong C, Di Liu, Shi W, Li M, Liu S, Chen J, Chen G, Li Y, Yang G, Lei Y, Xiong Y, Lei F, Wang H, Chen Q#, Chen J#, Gao GF. Novel avian influenza A (H5N6) viruses isolated in migratory waterfowl before the first human case reported in China, 2014. Sci Rep. 2016 Jul 19;6:29888.

16.Chen Y*, Ding Z, Liu X*, Chen J*, Li J, Fei Y, Liu Z, Stoeger T, Bi Y, Yin R. Biological and phylogenetic characterization of a novel hemagglutination-negative avian avulavirus 6 isolated from wild waterfowl in China. Transbound Emerg Dis. 2018 Aug 26.

17.Yao Y, Zhang T, Yang W, Shao Z, He B, Chen X, Wu L, Jin E, Liu H, Chen J#, Chen J#. Avian Influenza A (H7N9) Virus in a Wild Land Bird in Central China, Late 2015. Virol Sin. 2018 Feb;33(1):96-99.

18.Yin R, Zhang P, Liu X, Chen Y, Tao Z, Ai L, Li J, Yang Y, Li M, Xue C, Qian J, Wang X, Chen J, Li Y, Xiong Y, Zhang J, Stoeger T, Bi Y, Chen J#, Ding Z#. Dispersal and Transmission of Avian Paramyxovirus Serotype 4 among Wild Birds and Domestic Poultry. Front Cell Infect Microbiol. 2017 May 26;7:212.

19.Bi Y*, Chen J*, Zhang Z, Li M, Cai T, Sharshov K, Susloparov I, Shestopalov A, Wong G, He Y, Xing Z, Sun J, Liu D, Liu Y, Liu L, Liu W, Lei F, Shi W, Gao GF. Highly pathogenic avian influenza H5N1 Clade 2.3.2.1c virus in migratory birds, 2014-2015. Virol Sin. 2016 Aug;31(4):300-5.

20.Liu S, Li M, Su Z, Deng F#, Chen J#. A 3-year follow-up study of the seroprevalence of antibodies to avian influenza A H5, H6, H7 and H10 viruses among the general population of Wuhan, China. J Clin Virol. 2016 Apr;77:109-10.

21.Zhou CH, Wu Z, Chen JJ#, Xiong C, Chen Z, Pang DW, Zhang ZL#. Biometallization-Based Electrochemical Magnetoimmunosensing Strategy for Avian Influenza A (H7N9) Virus Particle Detection. Chem Asian J. 2015 Jun;10(6):1387-93.

22.Bi Y, Mei K, Shi W, Liu D, Yu X, Gao Z, Zhao L, Gao GF, Chen J#, Chen Q#. Two novel reassortants of avian influenza A (H5N6) virus in China. J Gen Virol. 2015 May;96(Pt 5):975-81.