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  • 姓名: 陈全姣
  • 性别: 女
  • 职称: 研究员(自然科学)
  • 职务: 研究员
  • 学历: 博士研究生
  • 电话: 027-87198167
  • 传真: 
  • 电子邮件: chenqj@wh.iov.cn
  • 所属部门: 流感病毒学科组
  • 通讯地址: 湖北省武汉市武昌小洪山中区44号

    简  历:

  •       陈全姣,博士,研究员。现任武汉病毒所流感病毒学科组长。1997年及2003年于华中农业大学动物医学学院获得学士及硕士学位,2007年于中国科学院武汉病毒研究所获博士学位。主要研究方向为自然感染状态下流感病毒的生物学特征;流感病毒感染致病机制及致死宿主细胞途径及分子细节;Nipah病毒致病机理。主持的项目(课题)包括科技部“973”项目子课题,国家科技重大专项,国家自然科学基金面上和青年基金,多项企业产品体内和体外抗流感病毒药效评价课题等。在Cell Host & Microbe, Clinical infectious diseases, Journal of Virology, Emerg Microbes Infect, Infect Genet Evol和J Gen Virol等国际学术期刊发表代表性通讯作者论文。曾获山东省科学技术二等奖。    

    社会任职:

    研究方向:

  • 自然感染状态下流感病毒的生物学特征;流感病毒感染致病机制及致死宿主细胞途径及分子细节;新型流感病毒疫苗设计。

    承担科研项目情况:

    代表论著:

  •     

    1.        Ma L, Jin T, Wang H, Liu H, Wang R, Li Y, Yang G, Xiong Y, Chen J, Zhang J, Chen G, Li W, Liu D, Lin P, Huang Y, Gao GF, Chen Q*. Two reassortant types of highly pathogenic H5N8 avian influenza virus from wild birds in Central China in 2016.

           Emerg Microbes Infect. 2018 Feb 7;7(1):14.

    2.        Bi Y, Chen Q*, Wang Q, Chen J, Jin T, Wong G, Quan C, Liu J, Wu J, Yin R, Zhao L, Li M, Ding Z, Zou R, Xu W, Li H, Wang H, Tian K, Fu G, Huang Y, Shestopalov A, Li S, Xu B, Yu H, Luo T, Lu L, Xu X, Luo Y, Liu Y, Shi W, Liu D, Gao GF. Genesis, Evolution and Prevalence of H5N6 Avian Influenza Viruses in China. Cell Host Microbe. 2016 Dec 14;20(6):810-821.

    3.        Chen Q*, Wang H, Zhao L, Ma L, Wang R, Lei Y, Li Y, Yang G, Chen J, Chen G, Li L, Jin T, Li J, Liu X, Xu X, Wong G, Liu L, Liu Y, Shi W, Bi Y, Gao GF. First documented case of avian influenza (H5N1) virus infection in a lion.  Emerg Microbes Infect. 2016 Dec 21;5(12):e125.

    4.        Bi Y, Liu H, Xiong C, Di Liu, Shi W, Li M, Liu S, Chen J, Chen G, Li Y, Yang G, Lei Y, Xiong Y, Lei F, Wang H, Chen Q*, Chen J, Gao GF. Novel avian influenza A (H5N6) viruses isolated in migratory waterfowl before the first human case reported in China, 2014. Sci Rep. 2016 Jul 19;6:29888.

    5.        Mei K, Liu G, Chen Z, Gao Z, Zhao L, Jin T, Yu X, Chen Q*. Deep sequencing reveals the viral adaptation process of environment-derived H10N8 in mice.  Infect Genet Evol. 2016 Jan; 37:8-13.

    6.        Bi Y, Xiao H, Chen Q*, Wu Y, Fu L, Quan C, Wong G, Liu J, Haywood J, Liu Y, Zhou B, Yan J, Liu W, Gao GF.Changes in the Length of the Neuraminidase Stalk Region Impact H7N9 Virulence in Mice. J Virol. 2015 Dec 9;90(4):2142-9.

    7.        Bi Y, Mei K, Shi W, Liu D, Yu X, Gao Z, Zhao L, Gao GF, Chen J, Chen Q*. Two Novel Reassortants of Avian Influenza A(H5N6) Virus in China. J Gen Virol. 2015, 96(Pt 5): 975-81. 

    8.        Wang B, Liu Z, Chen Q*, Gao Z, Fang F, Chang H, Chen J, Xu B, Chen Z. Genotype diversity of H9N2 viruses isolated from wild birds and chickens in Hunan Province, China. PLoS One. 2014 Jun 30;9(6):e101287.

    9.        Sui Z, Wen B, Gao Z, Chen Q*. Fusion-related host proteins are actively regulated by NA during influenza infection as revealed by quantitative proteomics analysis. PLoS One. 2014 Aug 25;9(8):e105947.

    10.    Chen Q*, Huang S, Chen J, Zhang S, Chen Z*. NA proteins of influenza A viruses H1N1/2009, H5N1, and H9N2 show differential effects on infection initiation, virus release, and cell-cell fusion. PLoS One. 2013; 8(1): e54334.

    专利申请:

    获奖及荣誉: